Anne-Julie Tessier

Son domaine d'expertise porte sur l'impact de la nutrition sur la longévité en santé, en particulier sur la santé musculaire et cérébrale. Elle intègre des technologies innovantes telles que la métabolomique, la protéomique et les applications mobiles pour mieux comprendre les mécanismes sous-jacents et pour identifier des biomarqueurs nutritionnels. Son objectif est de contribuer au développement de stratégies nutritionnelles personnalisées pour promouvoir la santé à long terme et prévenir les maladies liées au vieillissement. Ses travaux englobent des études épidémiologiques traditionnelles, intégrant la métabolomique et la protéomique plasmatiques et cérébrales, des essais d'intervention, ainsi que des études de validation.

Dre Anne-Julie Tessier est Professeure adjointe au Département de nutrition de l'Université de Montréal, chercheuse au Centre ÉPIC de l'Institut de cardiologie de Montréal et chercheuse invitée à la Harvard T.H. Chan School of Public Health. Nutritionniste-diététiste (membre de l'ODNQ), elle a obtenu son doctorat en nutrition humaine à l'Université McGill, suivi d'une formation postdoctorale soutenue par les IRSC (Instituts de recherche en santé du Canada) et d'un poste de chercheuse associée à la Harvard T.H. Chan School of Public Health.

• Postdoctorat, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA
• Ph.D, School of Human Nutrition, McGill University, Montreal, QC, Canada
• B.Sc, School of Human Nutrition, McGill University, Montreal, QC, Canada

• 22-06-2022 Une médaille d’or du Gouverneur général et plus encore pour Anne-Julie Tessier

• Tessier AJ, Glenn A, Wang F, Eliassen AH, Zeleznik O, Stampfer M, Rexrode K, Tobias D, Manson J, Clish C, Liu S, Chavarro J, Hu F, Guasch M. Metabolomic Profiles of Plant and Animal Protein and Type 2 Diabetes: Four Prospective US Cohort Studies. Res Sq [Preprint]. 2026 Aug 26:rs.3.rs-10525472. doi: 10.21203/rs.3.rs-10525472/v1. PMID: 42687954; PMCID: PMC13532719.
• Hu F, Wang F, Tessier AJ, Glenn A, Liu Y, Guasch-Ferré M, Tobias D, Eliassen AH, Manson J, Clish C, Lee KH, Shai I, Qi Q, Burk R, Liang L, Sun Q, Kaplan R, Willett W, Wang D. Epidemiological and Multi-Omics Investigation of Phytosterol Intake and Type 2 Diabetes Risk. Res Sq [Preprint]. 2026 Apr 2:rs.3.rs-9222420. doi: 10.21203/rs.3.rs-9222420/v1. PMID: 41960322; PMCID: PMC13060520.
• Chen H, Cortese M, Flores-Torres MH, Tessier AJ, Wang DD, Kang JH, Eliassen AH, Stampfer M, Ascherio A, Willett W, Yuan C, Bjornevik K. Dietary Patterns and Indicators of Cognitive Function. JAMA Neurol. 2026 Apr 1;83(4):382-391. doi: 10.1001/jamaneurol.2026.0062. PMID: 41729538; PMCID: PMC12931470.
• Tessier AJ, Wang F, Korat AA, Eliassen AH, Chavarro J, Grodstein F, Li J, Liang L, Willett WC, Sun Q, Stampfer MJ, Hu FB, Guasch-Ferré M. Optimal dietary patterns for healthy aging. Nat Med. 2025 May;31(5):1644-1652. doi: 10.1038/s41591-025-03570-5. Epub 2025 Mar 24. PMID: 40128348; PMCID: PMC12092270.
• Moyen A, Rossi A, Hart M, Simons E, Mandhane PJ, Moraes TJ, Azad MB, Turvey SE, Subbarao P, Tessier AJ*, Miliku K. Measuring diet intake in adolescents: Relative validation of an artificial intelligence enhanced, image assisted mobile application. Clin Nutr. 2026 Feb;57:106568. doi: 10.1016/j.clnu.2025.106568. Epub 2026 Jan 3. PMID: 41512632. *co-senior
• Birukov A, Lin N, Mongiovi J, Razquin C, Wang F, Semnani-Azad Z, Tessier AJ, Guasch-Ferré M, Ley SH, Manson JE, Sinkey RG, Haring B, Shadyab AH, Balasubramanian R, Martínez-González MA, Rexrode KM, Hu FB, Zhang C, Zeleznik OA, Sasamoto N. Plasma metabolomic signature of breastfeeding and risk of cardiometabolic diseases. Nat Commun. 2025 Dec 8;16(1):11124. doi: 10.1038/s41467-025-65977-5. PMID: 41360798; PMCID: PMC12706040.
• Dionne V, Iglesies-Grau J, Latour É, Besnier F, Gagnon C, Gayda M, Pelletier V, Selcer S, Vrinceanu T, Debray A, Tessier AJ, Juneau M, Nigam A, L'Allier PL, Bherer L. Optimizing cardiovascular health with a type 2 diabetes remission program: Ultraprocessed food-intake reduction, Mediterranean diet, chrononutrition and physical training-The DIABEPIC-2 pilot study. Diabetes Obes Metab. 2025 Dec;27(12):7374-7384. doi: 10.1111/dom.70142. Epub 2025 Sep 18. PMID: 40968544.
• Prokopidis K, Tessier AJ, Ragusa FS, Ferrini K, Garlisi MC, Testa GD, Barbagallo M, Veronese N. Comprehensive geriatric assessment markers in older adults with and without sarcopenia: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2025 Nov;138:105982. doi: 10.1016/j.archger.2025.105982. Epub 2025 Aug 6. PMID: 40812083.
• Glenn AJ, Tessier AJ, Kavanagh ME, Morgan GA, Clish CB, Salas-Salvado J, Malik VS, Hanley AJ, Bazinet RP, Comelli EM, El-Sohemy A, Liu S, Boucher BA, Kendall CWC, Jenkins DJA, Hu FB, Sievenpiper JL. Metabolomic profiling of a cholesterol lowering plant-based diet from two randomized controlled feeding trials. Eur J Clin Nutr. 2025 Sep;79(9):863-875. doi: 10.1038/s41430-025-01625-x. Epub 2025 Apr 22. PMID: 40263496.
• Tessier AJ, Wang F, Korat AA, Eliassen AH, Chavarro J, Grodstein F, Li J, Liang L, Willett WC, Sun Q, Stampfer MJ, Hu FB, Guasch-Ferré M. Optimal dietary patterns for healthy aging. Nat Med. 2025 May;31(5):1644-1652. doi: 10.1038/s41591-025-03570-5. Epub 2025 Mar 24. PMID: 40128348; PMCID: PMC12092270.
• Guasch-Ferré M, Pacheco LS, Tessier AJ, Li Y, Willett WC, Sun Q, Salas-Salvadó J, Martínez-González MA, Stampfer MJ, Hu FB. Changes in olive oil consumption and long-term body weight changes in 3 United States prospective cohort studies. Am J Clin Nutr. 2025 May;121(5):1149-1156. doi: 10.1016/j.ajcnut.2025.02.012. Epub 2025 Feb 18. PMID: 39978469; PMCID: PMC12107489.
• D'Amico D, Savundranayagam MY, Biles R, Itzhak I, Anderson ND; Canadian Consortium on Neurodegeneration in Aging (CCNA) CAN-THUMBS UP Study Group. Engaging older adults in the process of aging research: a multimethod study evaluating the experience and efficacy of a citizen advisory group for a dementia risk reduction program. Res Involv Engagem. 2024 Dec 27;10(1):135. doi: 10.1186/s40900-024-00643-6. PMID: 39731188; PMCID: PMC11674478.
• Glenn AJ, Wang F, Tessier AJ, Manson JE, Rimm EB, Mukamal KJ, Sun Q, Willett WC, Rexrode KM, Jenkins DJ, Hu FB. Dietary plant-to-animal protein ratio and risk of cardiovascular disease in 3 prospective cohorts. Am J Clin Nutr. 2024 Dec;120(6):1373-1386. doi: 10.1016/j.ajcnut.2024.09.006. PMID: 39631999; PMCID: PMC12121410.
• Iglesies-Grau J, Dionne V, Latour É, Gayda M, Besnier F, Gagnon D, Debray A, Gagnon C, Tessier AJ, Paradis A, Klai C, Martin N, Pelletier V, Simard F, Nigam A, L'Allier PL, Juneau M, Bouabdallaoui N, Bherer L. Cardiac Rehabilitation for Prediabetes and Metabolic Syndrome Remission: Impact of Ultraprocessed Food-Intake Reduction and Time-Restricted Eating in the DIABEPIC-1 Study. CJC Open. 2024 Aug 10;6(11):1411-1421. doi: 10.1016/j.cjco.2024.07.018. PMID: 39582705; PMCID: PMC11583856.
• Wang, F.,   Glenn, A.J., Tessier, A-J.,  Mei Z., Haslam D.E., Guasch-Ferré M., Tobias, D.K., Eliassen, A.H., Manson, J.E., Clish, C.,   Lee, K.H.,  Rim, E.B., Wang, D.D., Sun, Q., Liang, L., Willett, W.C., Hu, F.B. Heme iron intake and increased type 2 diabetes risk revealed by integrated epidemiological and biomarker analysis. Nat Metab. 10.1038/s42255-024-01109-5 (FI: 18.9)
• Tessier, A-J., Cortese, M., Yuan, C., Bjornevik, K., Ascherio, A., Chavarro, J.E., Stampfer, M.J., Hu, F.B., Willett, W., Guasch-Ferré, M. Olive oil intake and the risk of fatal dementia: two large prospective cohort studies, JAMA Netw Open, doi:10.1001/jamanetworkopen.2024.10021 (FI: 13.8).
• Tessier, A-J., Wang, F., Liang, L., Wittenbecher, C., Haslam, D.E., Eliassen, H.A., Tobias, D.K., Li, J., Zeleznik, O., Ascherio, A., Sun, Q., Stampfer, M.J., Grodstein, F., Rexrode, K.M., Manson, J.E., Balasubramanian, R., Clish, C.B., Martinez-Gonzalez, M.A., Chavarro, J.E., Hu, F.B., Guasch-Ferré, M. Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: four prospective U.S. cohort studies, Med (Cell Press), doi : 10.2139/ssrn.4484650 (FI : 17).
• Wang, F., Tessier, AJ., Liang, L., Wittenbecher, C., Haslam, D.E., Eliassen, H.A., Rexrode, K.M., Tobias, D.K., Li, J., Zeleznik, O., Stampfer, M.J., Grodstein, F., Martinez-Gonzalez, M.A., Salas-Salvado, J., Clish, C., Lee, KH., Sun, Q., Hu, F.B., Guasch-Ferré, M.  Plasma metabolomics profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals. Nat Comm. doi: 10.1038/s41467-023-41515-z (IF: 17.69)
• Canadian Consortium on Neurodegeneration in Aging (CCNA) CAN-THUMBS UP Study. Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A prospective 12-month intervention study. J Prev Alzheim, doi: 10.14283/jpad.2023.65 (IF: 4.47).
• Tessier A-J, Moyen, A., Lawson, C., Rappaport A.I, Yousif, I., Fleurent-Grégoire, C., Lalonde-Bester, S., Brazeau A-S, Chevalier S. Lifestyle behavior changes and associated risk factors during the COVID-19 pandemic: results from the Canadian COVIDiet online cohort study. JMIR Public Health Surveill 2023, doi:  10.2196/43786 (IF:  14.6)
• Guasch-Ferré, M., Tessier A-J, Petersen, KS., Sapp, PA., Tapsell, LC., Salas-Salvado, J., Ros, E., Kris-Etherton, PM. Effects of nut consumption on blood lipids and lipoproteins: a comprehensive literature update. Nutrients 2023, doi: 10.3390/nu15030596 (IF: 5.72)
• Moyen, A., Rappaport A., Tessier A-J, Brazeau A-S, Chevalier S. Relative validation of an artificial intelligence-enhanced, image-assisted mobile application for dietary assessment in adults: a randomized, cross-over study. JMIR 2022, doi: 10.2196/40449 (IF: 7.08)
• Tessier A-J, Wing SS, Rahme E, Morais JA, Chevalier S. Low muscle mass is independently associated with faster executive function decline over 3 years in older adults from the Canadian Longitudinal Study on Aging. JAMA Network Open 2022, doi:10.1001/jamanetworkopen.2022.19926 (IF: 13.35)
• Tessier A-J., Lévy-Ndejuru J., Moyen A., Lawson M, Morais JA., Bhullar A., Andriamampionona F., Mazurak VC., Chevalier S. A 16-week randomised controlled trial of a fish oil and whey protein-derived supplement to improve physical performance in older adults losing autonomy – a pilot study. PLoS ONE 2021, doi: 10.1371/journal.pone.0256386 (IF: 3.24)
• Tessier A-J., Presse N., Ferland G., Bherer L., Chevalier S.  Milk, yogurt and cheese intake is associated with cognitive executive functions in older adults of the Canadian Longitudinal Study on Aging. J Gerontol A Biol Sci Med Sci 2021, doi: 10.1093/gerona/glab165 (IF: 6.05)
• Tessier A-J., Wing S. S., Rahme E., Morais J.A., Chevalier, S. Physical function-derived cut-points for the diagnosis of sarcopenia and dynapenia from the Canadian longitudinal study on aging. J Cachexia Sarcopenia Muscle 2019, doi: 10.1002/jcsm.12462 (IF : 12.9)
• Tessier A.-J., Chevalier S. Comment on viewpoint: Uprooting sarcopenia from its origins by introducing body fat to its definition. J Appl Physiol 2019, doi:10.1152/japplphysiol.00816.2018 (IF: 3.05)
• Tessier, A-J., Chevalier, S. An update on protein, leucine, omega-3 fatty acids, and vitamin D in the prevention and treatment of sarcopenia and functional decline. Nutrients 2018,  doi: 10.3390/nu10081099 (IF: 5.72)